
Cascara Sagrada bark
Cascara sagrada is the dried bark of a buckthorn tree that grows along the Pacific coast of North America. Its name is Spanish for “sacred bark.”
Its anthraquinones prompt the colon wall to push stool along. FDA ruled in 2002 that cascara is not generally recognized as safe and effective as an OTC laxative, because the safety data it asked for never arrived (FDA, 2002).
Case reports link it to liver injury that mostly cleared after stopping (LiverTox, Cascara).












